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Muscle conditions in women

Your muscles move and steady your body. Autoimmune muscle disease shows up as true weakness, not just soreness.

Illustration of a nerve meeting a muscle fiber
Illustration: Servier Medical Art, CC BY 4.0 (resized)

Conditions that affect your muscles 8

Autoimmune and chronic conditions that can involve your muscles. Each guide covers early signs, labs to ask about, and when to see a doctor.

Dermatomyositis & myositis

Autoimmune

Autoimmune conditions in which the immune system inflames the muscles, causing weakness. Dermatomyositis also causes a distinctive rash.

MusclesSkinLungs

Fatigue and chronic fatigue

Chronic

Ongoing exhaustion that limits daily life. It can come from a treatable cause, or it can be ME/CFS, a serious illness in which effort makes symptoms worse.

MusclesBrain & nervesBlood & immune system

Myasthenia gravis

Autoimmune

Antibodies block the signal between nerves and muscles, causing weakness that gets worse with use and improves with rest.

MusclesBrain & nervesEyes & mouth

Polymyalgia rheumatica

Autoimmune

An immune-mediated inflammatory condition that causes pain and stiffness in the shoulders, neck, and hips, almost always after age 50.

MusclesJointsBlood & immune system

Osteoarthritis

Chronic

The most common type of arthritis. The cartilage that cushions the ends of bones breaks down over time, causing pain and stiffness, most often in the knees, hips, hands, and spine.

JointsMuscles

Rheumatologic conditions

Chronic

Rheumatology covers conditions of the joints, muscles, bones, and connective tissue, and many of them are autoimmune. This overview explains how inflammatory joint pain differs from mechanical pain, and where to read about specific conditions.

JointsMusclesBlood & immune systemSkin

Mixed connective tissue disease

Autoimmune

An overlap condition with features of lupus, scleroderma, and myositis, marked by high levels of an antibody called anti-U1 RNP.

JointsSkinMusclesLungsBlood & immune system

Chronic infections

Chronic

Ongoing symptoms that follow or are linked to an infection or exposure. Some links are well established, and others are still debated.

Blood & immune systemBrain & nervesJointsMuscles

Signs worth getting checked

  • Trouble climbing stairs, rising from a chair, or lifting your arms overhead
  • Weakness that gets worse the more you use a muscle
  • Drooping eyelids or double vision
  • Muscle pain with dark, tea-colored urine (get same-day care)

Ingredients that affect your muscles

Vitamins, minerals, herbs, and other supplements commonly used for the muscles. Each one links to its full guide.

About your muscles

What it does

Muscles contract when a nerve releases a chemical signal at the point where nerve meets muscle. Muscle also stores energy, helps regulate blood sugar, and protects your bones and joints.

Common issues

  • Tension and knots from stress and posture
  • Cramps from low magnesium or dehydration
  • Aches with low vitamin D or thyroid problems
  • Muscle pain as a side effect of statins
  • Fibromyalgia
Dr. Lesher, ND

Wondering if your symptoms fit a pattern?

Dr. Lesher is a naturopathic doctor who specializes in women's autoimmune and chronic conditions. Since 2020, she has helped more than 900 patients overcome and heal from their conditions.

Book a consult now