Pantothenic acid (B5)
Also called: Vitamin B5, calcium pantothenate, pantethine
Used to make coenzyme A, which cells need to make energy, fats, and some hormones. It's found in so many foods that deficiency is rare.
Commonly used for
- Energy metabolism
- Stress and adrenal formulas (evidence is limited)
- Cholesterol and triglycerides (pantethine, some studies)
- Acne (one small study)
Found naturally in
- Shiitake mushrooms
- Avocado
- Eggs
- Chicken
- Sunflower seeds
Label red flags
- Adrenal or stress formulas that pair B5 with herbs or glandular extracts. Check every ingredient.
- Large amounts sold for acne, which can cause loose stools
Check with a provider
- Taking cholesterol medicine and considering pantethine
- Pregnant or breastfeeding. The amount in a prenatal is fine. Ask before adding more.
- Diarrhea or stomach upset, which can happen with large amounts
Supplements that contain it
Parts of the body it affects
Explore what each area does and the conditions that can affect it.
Adrenal glands
These small glands on top of your kidneys make cortisol, aldosterone, and adrenaline, which manage energy, blood pressure, and your stress response.
Skin
Your skin is your largest organ and a major immune barrier. Rashes, patches, and color changes are often the first visible signs of an autoimmune condition.
Illustrations: Servier Medical Art, CC BY 4.0
Wondering if your symptoms fit a pattern?
Dr. Lesher is a naturopathic doctor who specializes in women's autoimmune and chronic conditions. Since 2020, she has helped more than 900 patients overcome and heal from their conditions.