Evening primrose oil
Also called: EPO, GLA (gamma-linolenic acid)
A seed oil rich in GLA, an omega-6 fat the body uses to make anti-inflammatory compounds. Evidence for most uses is mixed.
Commonly used for
- Cyclical breast pain (mixed evidence)
- PMS (limited evidence)
- Dry skin
- Joint stiffness (GLA, some studies)
Found naturally in
- Few foods contain GLA
- Your body makes GLA from linoleic acid in seed oils
- Hemp seeds
- Spirulina
Label red flags
- No GLA content listed
- Borage oil not labeled as free of pyrrolizidine alkaloids (PA-free)
- A strong or rancid smell, which suggests the oil has oxidized
Check with a provider
- Pregnancy. Avoid unless your practitioner directs it.
- Seizure disorder, or taking medicines that can lower the seizure threshold, such as phenothiazines
- Taking blood thinners or antiplatelet drugs, or having surgery soon
- Bleeding disorders
Supplements that contain it
Parts of the body it affects
Explore what each area does and the conditions that can affect it.
Skin
Your skin is your largest organ and a major immune barrier. Rashes, patches, and color changes are often the first visible signs of an autoimmune condition.
Reproductive organs
Your ovaries and uterus shape your cycle, fertility, and hormones. Sex hormones also influence the immune system, one reason autoimmune disease is more common in women.
Illustrations: Servier Medical Art, CC BY 4.0
Wondering if your symptoms fit a pattern?
Dr. Lesher is a naturopathic doctor who specializes in women's autoimmune and chronic conditions. Since 2020, she has helped more than 900 patients overcome and heal from their conditions.